Auto-SCT in refractory celiac disease type II patients unresponsive to cladribine therapy
نویسندگان
چکیده
منابع مشابه
Evaluation of Cladribine treatment in refractory celiac disease type II.
AIM To evaluate cladribine [2-chlorodeoxyadenosine (2-CdA)] therapy in refractory celiac disease (RCD) II. METHODS An open-label cohort-study of RCD II patients treated with 2-CdA was performed between 2000 and 2010. Survival rate, enteropathy associated T-cell lymphoma (EATL) occurrence, clinical course, and histological and immunological response rates were evaluated. RESULTS Overall, 32 ...
متن کاملRefractory Celiac Disease
Refractory celiac disease (RCD) is when malabsorption symptoms and villous atrophy persist despite strict adherence to a gluten free diet (GFD) for more than 12 months and other causes of villous atrophy have been ruled out. RCD is considered a rare disease and almost exclusively occurs in adults. Persistent diarrhea, abdominal pain, weight loss are the most common symptoms in RCD. Also, anemi...
متن کاملEvaluation of the Relationship Between Celiac Disease and Refractory Epilepsy in Patients Referring to Imam Khomeini Hospital, Urmia
Introduction: Celiac disease can be associated with other diseases, including neurological disorders. In this study, the relationship between celiac disease and refractory epilepsy was evaluated in patients who were referred to Imam Khomeini Hospital in Urmia. Methods: In this cross-sectional study, patients with refractory epilepsy who were referred to the neurology clinic of Imam Khomeini Ho...
متن کاملRefractory Celiac Disease Type II: A Case Report that Demonstrates the Diagnostic and Therapeutic Challenges
Refractory celiac disease is an uncommon but serious complication of celiac disease. We describe a case of a severe refractory celiac disease type II, complicated with ulcerative jejunoileitis, in a 68 years old female, unresponsive to consecutive treatments with budesonide, prednisolone, cladribine and autologous stem cell transplantation. The patient maintained severe malnutrition, advanced o...
متن کاملrefractory celiac disease
refractory celiac disease (rcd) is when malabsorption symptoms and villous atrophy persist despite strict adherence to a gluten free diet (gfd) for more than 12 months and other causes of villous atrophy have been ruled out. rcd is considered a rare disease and almost exclusively occurs in adults. persistent diarrhea, abdominal pain, weight loss are the most common symptoms in rcd. also, anemi...
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ژورنال
عنوان ژورنال: Bone Marrow Transplantation
سال: 2010
ISSN: 0268-3369,1476-5365
DOI: 10.1038/bmt.2010.199